The Shoklo Malaria Research Unit (SMRU) -, is a field station of the Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand, and is part of the Mahidol-Oxford Research Unit supported by the Wellcome Trust (UK).

The SMRU was initially based in Shoklo camp (120 km north of Mae Sot) but moved to Mae La camp in 1996. In Mae La camp there wa one inpatient department, four outpatient departments, antenatal clinics, a delivery unit, diagnostic laboratory, a computing area and staff accommodation. The administrative office based in Mae Sot provided logistical support and a research laboratory was established. Mae Sot and Mae La were linked by radio. Since 1996, mains electricity became available to the SMRU in Mae La camp. The continued importance of malaria, the ability to follow-up the patients’ progress in the camp, and the excellent cooperation with the community made the site an ideal location to conduct field based studies

SMRU provides health care to the marginalized populations living on both sides of the Thai-Myanmar border in the Mae Sot area, Tak Province. This is achieved by the dual activities of research and humanitarian services, with an emphasis on maternal-health and infectious diseases. The combination of health care and research makes SMRU unique in that the research agenda is driven by questions faced in the clinical practice, whether clinical or laboratory based and the studies are designed to be of relevance to the population served.